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CannabisWhole Plant better than isolated molecules?

December 12, 2020by admin

Whole plant cannabinoids being more beneficial than single isolate cannabinoids

In the recent times, the cannabis plant has gained significant importance in medical and health care sector due to the presence of a range of beneficial cannabinoids. These cannabinoids interact with natural endocannabinoid system of human beings and animals and produces soothing, and calming effects. CBD and other cannabinoids are non-psychoactive compounds and do not make people high, whereas, THC has psychoactive effects and is being used for recreational purposes as well. Therefore, majority of cannabinoid consumers prefer to use CBD products only to avoid any potential side effects. While, an optimal and prescribed use of whole plant cannabinoids is more effective to deal with various body conditions and to promote overall health, and wellness. Therefore, this article is mainly focused to highlight the beneficial effects of consuming whole plant cannabinoids rather than the single isolate cannabinoids.

Cannabis plant contains various cannabinoids, and these are:

THC (Δ9–tetrahydrocannabinol)
CBG (Cannabigerol)
CBD (Cannabidiol)
CBGV (Cannabigerivarin)
CBC (Cannabichromene)
CBDV (Cannabidivarin)
THCV (Tetrahydrocannabivarin)
CBCV (Cannabichromevarin)

The cannabis plant is a natural miracle as it contains hundreds of bioactive compounds and their synergy have been regarded as entourage effect by the scientists and researchers. Whole plant cannabinoids can target more body parts than the single cannabinoids and their optimal intake is greatly important to get immediate relief. The synergistic effects of these cannabinoids are also helpful to balance psychoactive effects caused by THC.

Two professors Shimon Ben-Shabat, and  Raphael Mechoulam posited in 1998 that endocannabinoid system demonstrates entourage effects and thereby increases the activity of inactive metabolites and other related molecules. It was also postulated that this method can be used to improve the efficacy of drugs than the consumption of single isolated cannabinoids. Although, the synthesis of single-molecule cannabis products is a dominant model for the development of pharmaceutical products but the approach of botanical synergy can be used to invoke contributions of major and minor cannabinoids.

A scientific study conducted in the randomized and controlled trial of cannabis-based extracts has revealed that can optimize the opioid treatment. Significantly better results were produced followed by the combination of cannabinoids.

A recent study conducted by leading researchers has demonstrated that whole-plant cannabinoids can produce significantly effective results than the single cannabinoid THC. The efficiency of treatment was further improved by the addition of THCA, and CBG. The results of scientific studies have laid a solid foundation for cannabinoids synergy and further support the development of botanical drugs than the single cannabinoid products.

THC is psychoactive and decarboxylated form of THCA, and acts as a partial agonist for CB1 and CB2 receptors. These receptors are present in the brain cells, bladder, lungs, heart, adrenal, reproductive, gastrointestinal, immune cells, and can produce significant beneficial results by interacting with whole-plant cannabinoids. Thus these cannabinoids can greatly improve the body functioning and metabolic reactions.

Whole plant cannabinoids offers multiple benefits to support and maintain the quality of life such as

It helps to support the digestive system, digestive processes, and maintains good health of gastrointestinal tract
It promotes, supports, and maintains the immunity systems, and overall health of human beings and animals
It eases the joint pain and discomfort due to daily activities
Supports good neurological functioning
Supports overall life quality and provide comfort

The effects of whole plant cannabinoid extracts are more obvious due to their abilities for targeting multiple body parts and muscles, improved adsorption rates of active ingredients, overcoming bacterial defensive mechanisms, and minimizing the side effects.

Relief from Pain

Cannabis plant contains numerous cannabinoids and consumption of whole plant cannabinoids is essentially helpful to get relief from pain associated with various body conditions and medical disorders. Most commonly these cannabinoids are being used to get instant relief from chronic and acute pain.

Helpful for Alcoholism

Whole plant cannabinoids are greatly helpful to deal with alcoholism as cannabis plant has a high safety profile and is much better than the alcohol. Although, consumption of these cannabinoids may not be 100% safe and risk-free but it is a smarter way to reduce alcoholism by substituting alcohol with cannabinoids.

Treatment of Parkinson’s disease and Tremors

An optimized and regular consumption of safe and high-quality cannabinoids is significantly helpful to treat Parkinson’s disease and reduces pain, and tremors. Moreover, it also helps to treat insomnia and help consumers to have sound and peaceful sleep. Scientific studies have reported that cannabinoids consumption helps to regulate the motor skills and endocannabinoid interactions in the patients.

Treatment of Inflammatory Bowel Disease

Whole plant cannabinoids are an ideal solution to offer relief to patients suffering from ulcerative colitis. These cannabinoids greatly improves the immune system and also interacts with the gut cells to improve its functioning. Furthermore, these are also helpful to block and restrict the entry of harmful compounds and bacteria causing inflammation of intestines.

Reduced Side Effects of Hepatitis Treatment

Hepatitis C is a dangerous disease and their treatments also exert significant side effects such as muscle aches, depression, fatigue, and nausea. However, the effectiveness of treatment and immunity system of the body can be essentially improved by using whole plant cannabinoid products. However, the quality and safety profile of these cannabinoids is a major concern and these products must be properly tested for safety and quality standards.

Relief from Multiple Sclerosis

Multiple sclerosis is a painful medical condition and make people feel anxious and annoying, and irritated. However, a regular and prescribed consumption of whole plant cannabinoids can offer relief from multiple sclerosis by reducing the pain associated with muscle contractions.

Reduced Pain Associated with Arthritis

Cannabinoid products are being used as topical products such as balms and creams and are greatly helpful to treat arthritis. Although, CBD and THC offers excellent benefits to treat the arthritis but consumption of whole plant cannabinoids is more helpful to offer immediate relaxing and calming effects.

Treatment of Alzheimer’s disease

Alzheimer’s disease is directly related to the cognitive degeneration, and it gets more obvious with age. However, the development of this disease can be slowed down by the regular and prescribed consumption of whole plant cannabinoids. These cannabinoids interact with the endocannabinoid system of human beings and animals and acts as a natural remedy for body protection. Moreover, these cannabinoids offers anti-inflammatory properties that help to reduce the brain inflammation.

Alleviation of Anxiety

Excessive consumption and misuse of whole-plant cannabinoids may cause anxiety but a regular use of well-monitored dose can alleviate the symptoms of stress and anxiety. Thus, it helps to relax and calm the patients.

Glaucoma Treatment

Glaucoma causes the development of additional pressure on eyes and especially eyeball that is quite painful. However, the applied pressure on the eyeball can be reduced by consuming safe, and high-quality whole plant cannabinoids.

Regulation of Seizures

Results of various scientific studies have proven that whole-plant cannabinoids are helpful to control and reduce seizures. Moreover, it is also helpful to treat epilepsy and seizures due to other medical conditions.

Treatment of Autism

Multiple cannabinoids in the cannabis plant are significantly helpful to control mood swings and relax the consumers. The results have been more obvious to treat and control autism in children, therefore whole plant cannabinoids can be used for people belonging to all age groups.

Cannabinoids rich extracts exert much better therapeutic effects than single CBD product and help to effectively treat various conditions. The effectiveness of whole plant cannabinoids have also been approved by anecdotal, clinical and lab evidences to reduce inflammations, spasms, pain, and other conditions.

Synergistic Effects of Cannabinoids

The working abilities of whole-plant cannabinoids helps to develop a clear cut correlation between pain-reducing responses and dosage and make it an ideal candidate for further medical use and clinical studies. Although, the effectiveness of single-molecule cannabinoid product is not questionable but the use of whole plant cannabinoid products is significantly more helpful to get desired results.

Increased awareness about the safety profile and controlled use of whole plant cannabinoids has almost spawned the cannabis industry. Moreover, there are significant ongoing efforts to improve the effectiveness of strains by various plant breeding efforts. Thus scientists and manufacturers are offering safe and effective concentrates with a broad spectrum of efficient cannabinoid profiles.

There is a great shift of interest in various parts of the globe to produce safe and high-quality cannabinoids. Thus farmers are cultivating cannabis in ever-increasing number of fields and farms. While, there are significant ongoing efforts to cultivate cannabis in the greenhouse conditions to get maximum production.

There are over thousands of research papers and review articles highlighting the importance and functioning of cannabinoids for human health and wellness and the majority of the data has been published in the recent years. Although, the research about cannabinoids and their interaction with human and animal bodies is at the initial stage, but research findings are indicating significantly beneficial effects of cannabinoids. At present majority of cannabis products are not approved by the Food and Drug Administration but there are significant ongoing efforts to regulate cannabis products. However, high quality and safe cannabis products can be purchased from reliable markets and online stores. Furthermore, people can also make cannabinoid edibles at home to get multiple health and wellness benefits.